Marinos C Dalakas Selected Research

Stiff-Person Syndrome (Stiff Man Syndrome)

1/2022	Stiff-person Syndrome and GAD Antibody-spectrum Disorders: GABAergic Neuronal Excitability, Immunopathogenesis and Update on Antibody Therapies.
1/2022	Long-term Effectiveness of IVIg Maintenance Therapy in 36 Patients With GAD Antibody-Positive Stiff-Person Syndrome.
1/2022	Autoimmune Neurogenic Dysphagia.
10/2021	Update on Intravenous Immunoglobulin in Neurology: Modulating Neuro-autoimmunity, Evolving Factors on Efficacy and Dosing and Challenges on Stopping Chronic IVIg Therapy.
1/2021	Limited Benefits Halt Enrollment in Hematopoietic Stem Cell Transplantation Trial for Stiff-Person Syndrome: Should There Be More to Come?
1/2021	GAD antibody-spectrum disorders: progress in clinical phenotypes, immunopathogenesis and therapeutic interventions.
8/2017	A double-blind, placebo-controlled study of rituximab in patients with stiff person syndrome.
1/2016	Efficacy of Intravenous Immunoglobulin in Neurological Diseases.
2/2015	Intravenous immunoglobulin in neurology--mode of action and clinical efficacy.
11/2013	Glycine receptor antibodies in stiff-person syndrome and other GAD-positive CNS disorders.

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Marinos C Dalakas Research Topics

Disease

28	Stiff-Person Syndrome (Stiff Man Syndrome) 01/2022 - 05/2004
26	Myositis (Idiopathic Inflammatory Myopathies) 01/2022 - 06/2003
26	Inclusion Body Myositis 01/2022 - 06/2003
26	Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) 01/2022 - 12/2002
21	Myasthenia Gravis 01/2022 - 05/2004
20	Dermatomyositis (Dermatopolymyositis) 01/2022 - 06/2003
19	Polyneuropathies (Polyneuropathy) 01/2022 - 05/2004
14	Inflammation (Inflammations) 04/2016 - 08/2003
13	Muscular Diseases (Myopathy) 01/2022 - 03/2003
11	Nervous System Diseases (Neurological Disorders) 01/2022 - 12/2005
10	Guillain-Barre Syndrome 01/2022 - 06/2002
9	Multiple Sclerosis 01/2022 - 05/2004
8	Polymyositis 12/2020 - 09/2003
8	Autoimmune Diseases (Autoimmune Disease) 11/2019 - 01/2006
7	Disease Progression 01/2022 - 08/2006
6	Limbic Encephalitis (Paraneoplastic Limbic Encephalitis) 01/2022 - 11/2013
6	Central Nervous System Diseases (CNS Diseases) 01/2022 - 05/2005
5	Spasm (Spasms) 01/2022 - 06/2005
5	Epilepsy (Aura) 01/2022 - 11/2013
5	Demyelinating Diseases (Demyelinating Disease) 01/2022 - 12/2002
5	Cerebellar Ataxia (Dysmetria) 01/2022 - 11/2013
5	Autoimmune Diseases of the Nervous System 01/2022 - 12/2014
5	COVID-19 01/2022 - 01/2020
5	Fibrosis (Cirrhosis) 01/2022 - 08/2005
5	Neuroinflammatory Diseases 11/2020 - 09/2006
5	Neurodegenerative Diseases (Neurodegenerative Disease) 11/2020 - 09/2006
5	Muscle Weakness 01/2020 - 02/2004
5	Neuromyelitis Optica (Devic's Disease) 12/2015 - 10/2006
5	Nonaka type Distal myopathy 03/2007 - 03/2004
4	Infections 01/2020 - 01/2015
4	Ataxia (Dyssynergia) 11/2019 - 03/2010
4	Neoplasms (Cancer) 11/2019 - 04/2011
4	Muscular Dystrophies (Muscular Dystrophy) 09/2015 - 02/2004
3	Deglutition Disorders (Dysphagia) 01/2022 - 11/2008
3	Fatigue 10/2021 - 04/2013
3	Alzheimer Disease (Alzheimer's Disease) 11/2020 - 09/2006
3	Brain Diseases (Brain Disorder) 11/2020 - 01/2018
3	Virus Diseases (Viral Diseases) 11/2019 - 04/2011
3	Pain (Aches) 01/2018 - 02/2005
3	Paraproteinemias (Monoclonal Gammopathy) 01/2018 - 01/2006
3	Relapsing-Remitting Multiple Sclerosis 01/2018 - 10/2008
2	Isaacs Syndrome (Neuromyotonia) 01/2022 - 01/2022
2	Amyloid Plaque 01/2022 - 11/2013
2	Necrosis 01/2022 - 09/2003
2	Common Cold 10/2021 - 01/2021
2	Peripheral Nervous System Diseases (PNS Diseases) 11/2020 - 10/2006
2	Coma (Comas) 11/2020 - 11/2019
2	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2020 - 12/2005
2	Thymoma (Thymic Carcinoma) 11/2019 - 12/2014
2	Seizures (Absence Seizure) 01/2018 - 01/2013
2	Experimental Autoimmune Neuritis 01/2018 - 06/2013
2	Headache (Headaches) 01/2018 - 09/2010
2	Cerebellar Diseases (Cerebellar Syndrome) 01/2017 - 09/2006
2	Optic Neuritis (Retrobulbar Neuritis) 08/2015 - 05/2004

Drug/Important Bio-Agent (IBA)

41	Intravenous Immunoglobulins (IVIG)FDA Link 01/2022 - 06/2002
36	AntibodiesIBA 01/2022 - 12/2002
22	Proteins (Proteins, Gene)FDA Link 01/2022 - 07/2003
19	AutoantibodiesIBA 01/2022 - 06/2004
16	Complement System Proteins (Complement)IBA 01/2022 - 09/2003
13	AntigensIBA 11/2019 - 06/2004
11	Amyloid (Amyloid Fibrils)IBA 01/2022 - 10/2004
10	Immunoglobulin G (IgG)IBA 01/2022 - 01/2013
10	CytokinesIBA 11/2020 - 12/2002
8	Rituximab (Mabthera)FDA Link 01/2022 - 10/2008
8	Monoclonal AntibodiesIBA 01/2022 - 08/2006
6	Glutamate Decarboxylase (Decarboxylase, Glutamate)IBA 01/2022 - 06/2004
6	Biomarkers (Surrogate Marker)IBA 01/2019 - 12/2006
6	DesminIBA 07/2009 - 03/2003
5	gamma-Aminobutyric Acid (GABA)IBA 01/2022 - 06/2005
5	Biological ProductsIBA 01/2022 - 08/2005
5	Immunoglobulin M (IgM)IBA 01/2018 - 06/2004
5	CaprylatesIBA 02/2012 - 02/2008
4	Cholinergic ReceptorsIBA 01/2022 - 12/2012
4	N-Acetylneuraminic Acid (Sialic Acid)IBA 01/2020 - 03/2004
4	IceIBA 01/2019 - 02/2008
4	Messenger RNA (mRNA)IBA 09/2015 - 05/2004
4	SteroidsIBA 08/2015 - 06/2003
4	Amyloid beta-PeptidesIBA 05/2008 - 10/2004
4	ChemokinesIBA 05/2008 - 08/2003
4	EnzymesIBA 12/2006 - 03/2004
3	Phosphotransferases (Kinase)IBA 01/2022 - 11/2005
3	Peptides (Polypeptides)IBA 10/2021 - 01/2015
3	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2018 - 03/2006
3	Immunosuppressive Agents (Immunosuppressants)IBA 01/2016 - 06/2003
3	Immunoglobulins (Immunoglobulin)IBA 07/2014 - 05/2009
3	Myelin-Associated GlycoproteinIBA 05/2012 - 05/2004
3	Pharmaceutical PreparationsIBA 10/2011 - 03/2010
2	Ligases (Synthetase)IBA 01/2022 - 12/2020
2	muskIBA 01/2022 - 10/2020
2	Contactin 1IBA 01/2022 - 01/2022
2	Immunoglobulin Fc FragmentsIBA 10/2020 - 11/2015
2	Antiviral Agents (Antivirals)IBA 11/2019 - 01/2018
2	Methotrexate (Mexate)FDA LinkGeneric 07/2015 - 05/2012
2	EpitopesIBA 01/2015 - 12/2005
2	Reverse Transcriptase InhibitorsIBA 04/2013 - 04/2013
2	NucleosidesIBA 04/2013 - 04/2013

Therapy/Procedure

43	Therapeutics 01/2022 - 12/2002
17	Immunotherapy 01/2022 - 05/2005
3	Plasmapheresis 03/2015 - 06/2011
2	Art Therapy 01/2016 - 06/2012